Nigel Gericke, Dr.

Funktion

Freelance Consultant

Institut

Research Associate, University of Johannesburg, South Africa

Kontakt

E-Mail an Nigel Gericke

Website

https://drgerickeconsulting.com

Projekte

Current:

  • Khwe medicinal plant use, northern Namibia

Past:

  • Ethnobotanical documentation of San plant uses; the ethnobotany of the Cape West Coast
  • Co-author of the books Medicinal Plants of South Africa ; People’s Plants : Useful Plants of Southern Africa

Fachgebiete/Forschungsinteressen

  • CNS active medicinal plants

Ausbildung

  • B.Sc Honours (Botany)
  • M.B.B.Ch (Medicine & Surgery)

Arbeitserfahrung

South Africa, Botswana, Namibia, Tanzania

Publikationen

  • Brendler, T., Brinckmann, J.A., Feiter, U., Gericke, N., Lang, L., Pozharitskaya, O.N., Shikov, A.N., Smith, M. and Wyk, B.E.V., 2021. Sceletium for Managing Anxiety, Depression and Cognitive Impairment: A Traditional Herbal Medicine in Modern-Day Regulatory Systems. Current Neuropharmacology, 19(9), pp.1384-1400.

  • Wightman, E.L., Jackson, P.A., Forster, J., Khan, J., Wiebe, J.C., Gericke, N. and Kennedy, D.O., 2020. Acute effects of a polyphenol-rich leaf extract of mangifera indica l.(zynamite) on cognitive function in healthy adults: A double-blind, placebo-controlled crossover study. Nutrients, 12(8), p.2194.

  • López-Ríos, L., Wiebe, J., Vega-Morales, T., & Gericke, N. 2020. Central nervous system activities of extract Mangifera indica L. Journal of Ethnopharmacology, 112996.

  • Wiebe JC., López-Ríos L., Vega-Morales T., Pérez-Machín R., Mateos CJ., Gericke N. 2019. Neurophysiological effects of a special extract of Cyperus esculentus L. (Cyperol). Journal of Herbal Medicine Research 4:34, 1-18. https://escipub.com/journal-of-herbal-medicine-research/
  • Gericke, N. 2019. The emerging science behind extract Mangifera indica (Zynamite). Food processing and ingredients 54(2), 99-105. [Japanese]
  • Vega-Morales, T., Mateos-Díaz, C., Pérez-Machín, R., Wiebe, J., Gericke, N.P., Alarcón, C. and López-Romero, J.M., 2019. Chemical composition of industrially and laboratory processed Cyperus esculentus rhizomes. Food Chemistry.

  • Gelabert-Rebato, M., Wiebe, J.C., Martín-Rincón, M., Gericke, N., Pérez-Valera, M., Curtelin, D., Galvan-Alvarez, V., Lopez-Rios, L., Morales-Alamo, D. and Calbet, J.A.L., 2018. Mangifera indica L. leaf extract in combination with luteolin or quercetin enhances VO2 peak and peak power output, and preserves skeletal muscle function during ischemia-reperfusion in humans. Frontiers in Physiology, 9, p.740.

  • Dimpfel, W., Wiebe, J., Gericke, N., and Schombert, L. 2018. Zynamite® (Mangifera indica Leaf Extract) and Caffeine Act in a Synergistic Manner on Electrophysiological Parameters of Rat Central Nervous System. Food and Nutrition Sciences, 9, 502-518.

  • Dimpfel, W., Franklin, R., Gericke, N. and Schombert, L., 2018. Effect of Zembrin® and Four of its Alkaloid Constituents on Electric Excitability of the Rat Hippocampus. Journal of Ethnopharmacology.

  • Gericke, N. Kabbo’s !Kwain. The past, present and future of kanna. Chapter in McKenna, D. et al. (Eds.) 2018. The Ethnopharmacological Search for Psychoactive Drugs, pp. 122-150. Synergetic Press, Santa Fe. ISBN-13: 978-0907791683

  • Dimpfel, W., Gericke, N., Suliman, S. and Dipah, G.N.C., 2017. Effect of Zembrin® on Brain Electrical Activity in 60 Older Subjects after 6 Weeks of Daily Intake. A Prospective, Randomized, Double-Blind, Placebo-Controlled, 3-Armed Study in a Parallel Design. World Journal of Neuroscience, 7, pp.140-171.

  • Gericke, O., Gericke, N. and Stein D. Sceletium tortuosum. Chapter in Gerbarg, P, Muskin P.R, and Brown, RP. 2017. Complementary and Integrative
    Treatments in Psychiatric Practice. American Psychiatric Association Press.

  • Ruiters, A.K., Gericke, N., Stander, M. and Van Wyk, B.E., 2016. The Apocynaceae as a major source of functional foods in Southern Africa. Planta Medica, 81(S 01), p.804.

  • Dimpfel, W., Gericke, N., Suliman, S. and Dipah, G.N.C. 2016. Psychophysiological Effects of Zembrin® Using Quantitative EEG Source Density in Combination with Eye-Tracking in 60 Healthy Subjects. A Double-Blind, Randomized, Placebo-Controlled, 3-Armed Study with Parallel Design. Neuroscience and Medicine, 7, 114-132.

  • Dimpfel, W., Dipah, G.N.C. and Gericke, N., 2016. EnkephaloVision: Anatomical Functionality Indicated by Ultrashort Transient Regional EEG Spectral Power Changes during Cognitive and Emotional Challenges. World Journal of Neuroscience, 6 (02), p.90.

  • Dimpfel, W., Schombert, L., & Gericke, N. 2016. Electropharmacogram of Sceletium tortuosum extract based on spectral local field power in conscious freely moving rats. Journal of Ethnopharmacology, 177, 140-147.

  • Simon Chiu, Hana Raheb, Kristen Terpstra, JoshVaughan, Michel Farina-Woodbury, Yves Bureau, Zack Cernovsky, Jirui Hou, John Copen, Mariwan Husni, Vladimir Badmeav, Ana Hategan, Mujeeb Shad, Zach Suntras, Nigel Gericke. 2015. Exploring Zembrin extract derived from South African plant, Sceletium tortuosum in targeting cAMP-driven phosphodiesterase (PDE) signaling in Alzheimer’s Disease: synthesis of evidence. International Journal of Mental Health & Psychiatry, 2015.

  • Murbach, Timothy S., Gábor Hirka, Ilona Pasics Szakonyiné, Nigel Gericke, and John R. Endres. 2014. A toxicological safety assessment of a standardized extract of Sceletium tortuosum (Zembrin®) in rats. Food and Chemical Toxicology (74): 190-199.

  • Simon Chiu, Nigel Gericke, Michel Farina-Woodbury, Vladimir Badmaev, Hana Raheb, Kristen Terpstra, Joalex Antongiorgi, Yves Bureau, Zack Cernovsky, Jirui Hou, Veronica Sanchez, Marrissa Williams, John Copen, Mariwan Husni, and Liz Goble.
    2014.Proof-of-Concept Randomized Controlled Study of Cognition Effects of the Proprietary Extract Sceletium tortuosum (Zembrin) Targeting Phosphodiesterase-4 in Cognitively Healthy Subjects: Implications for Alzheimer’s Dementia. Evidence Based Alternative and Complementary Medicine. Article ID 682014, 9 pages
    http://dx.doi.org/10.1155/2014/682014

  • Gericke, N. May-July 2014. Ethnobotanical records from a corporate expedition in South Africa in 1685. Herbalgram. Journal of the American Botanical Council No. 102: 48-61.

  • Terburg D, Syal S, Rosenberger LA, Heany S, Phillips N, et al. (2013) Acute effects of Sceletium tortuosum (Zembrin), a dual -HT reuptake and PDE4 inhibitor, in the human amygdala and its connection to the hypothalamus. Neuropsychopharmacology 38: 2708-2716.

  • Nell, Haylene, Mirna Siebert, Pashini Chellan, and Nigel Gericke. 2013. A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Trial of Extract Sceletium tortuosum (Zembrin) in Healthy Adults. Journal of Alternative and Complementary Medicine 19, no. 11 (2013): 898-904.
  • Mncwangi, Nontobeko, Weiyang Chen, Ilze Vermaak, Alvaro M. Viljoen, and Nigel Gericke. 2012. Devil’s Claw–a review of the ethnobotany, phytochemistry and biological activity of Harpagophytum procumbens. Journal of Ethnopharmacology Volume 143 (3): 755-771.

  • Shikanga, E. A., Hamman, J. H., Chen, W., Combrinck, S., Gericke, N., & Viljoen, A. M. 2012. In Vitro Permeation of Mesembrine Alkaloids from Sceletium tortuosum across Porcine Buccal, Sublingual, and Intestinal Mucosa. Planta Medica 78(3), 260.

  • Shikanga, E. A., Viljoen, A. M., Combrinck, S., Marston, A., & Gericke, N. 2012. The chemotypic variation of Sceletium tortuosum alkaloids and commercial product formulations. Biochemical Systematics and Ecology, 44, 364-373.

  • Gericke, N. Muthi to medicine. 2011. S.A. Journal of Botany 77, 850-856.

  • Harvey, A.L. and Gericke, N.P. Bioprospecting: Creating a Value for Biodiversity. In Pavlinov, I.Y. (Ed.) 2011. Research in Biodiversity – Models and Applications, 2011. InTech. ISBN 978-953-307-794-9.

  • Harvey, A. L., Young, L. C., Viljoen, A. M., & Gericke, N. P. 2011. Pharmacological actions of the South African medicinal and functional food plant Sceletium tortuosum and its principal alkaloids. Journal of Ethnopharmacology, 137(3), 1124-1129.

  • van Wyk, B.E, van Oudtshoorn, B. and Gericke, N. 2009. 2nd edition. “Medicinal Plants of South Africa”, Briza.

  • Gericke, N. and A.M Viljoen. 2008. Sceletium – a review update. J. Ethnopharmacology 119: 653-663.

  • Welford, L., M.E. Abad Jara, and N. Gericke. 2008. Tree of Life. The use of Marula Oil in Southern Africa. HerbalGram 79: 32-41.

  • Gericke, N. 2002. Plants, Products. and People : Southern African Perspectives. In: Iwu, M. and Wootton, J. (Eds.) Advances in Phytomedicine Volume 1. Ethnomedicine and Drug Discovery. Elsevier. Amsterdam.

  • Gericke, N. : 2001. Clinical application of selected South African medicinal plants. Aus J Med Herbalism 13 (1): 3-15.

  • van Wyk, B.E, and Gericke, N. 2000. “People’s Plants – A Guide to Useful Plants of Southern Africa”, Briza

  • Gericke, N. Indigenous Plant Medicines in South Africa. 2000. Diversity Vol 2. No. 2, June – August.

  • Gericke, N. Regulation and Control of Traditional Herbal Medicines. In Iwu, M. et al. (Eds.).1997. Commercial Production of Phytomedicines and Cosmetics from Indigenous Plants. Bioresources Development and Conservation Programme.

  • Smith, M.T., N.R. Crouch, N. Gericke, M. Hirst. 1996. Psychoactive constituents of the genus Sceletium N.E. Br. and other Mesembryanthemaceae : a review. J. Ethnopharmacology 50:119-130.

  • Gericke, N. May 1996. Traditional Herbal Medicines. Modern Perspectives for South Africa. Health Trends. Journal of the South African Druggists Group. Pages 14-18.

  • Gericke, N. 1996. Key issues in the gathering, recording and development of indigenous knowledge. In: Norman, H. et al. (Eds.) Indigenous Knowledge And Its Uses In Southern Africa. Human Sciences Research Council, Pretoria.orem ips

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